The Topical Groups, composed of specialists from the participating countries, were created as forums for exchanging experiences and safety related information on particular topics agreed upon by the participating countries. Each Topical Group is led by a coordinator from one of the ANSN hubs. The participants in the Topical Groups assume the responsibilities to contribute to the development and implementation of the work plan of the Groups, to attend online and offline meetings, to contribute to the documentation of the results. The coordinators are responsible for establishing communication plan among the members and ensuring its operability, leading the preparation of the work plan and milestone schedule, calling online and offline meetings, assigning responsibilities for uploading documents to database and reporting to the SC Chairman